In the Eastern Mediterranean Region, there has been a rapid increase in the incidence of diabetes mellitus, mainly of type 2. It is now the fourth leading cause of death in the Region and an estimated 22 million people have diabetes out of a total adult population of 290 million. This quick reference guide aims to provide a readily accessible overview of the evidence-based facts regarding the management of hypertension patients with diabetes mellitus. They have been formulated to help improve the detection and management of hypertension in patients with diabetes mellitus, and hence decrease the associated microvascular and macrovascular complications.