Health research prioritization: global and regional perspectives

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Editorial

Ahmed Mandil,1 Arash Rashidian2 and Rana Hajjeh3

1Coordinator Research and Innovation, Department of Science, Information and Dissemination, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt. 2 Director, Department of Science, Information and Dissemination, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt. 3Director of Programme Management, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt. (Correspondence to: Arash Rashidian: This email address is being protected from spambots. You need JavaScript enabled to view it.).

Citation: Mandil A; Rashidian A; Hajjeh R. Health research prioritization: global and regional perspectives. East Mediterr Health J. 2020;26(3):254-256.

https://doi.org/10.26719/2020.26.3.254

Copyright © World Health Organization (WHO) 2020. Open Access. Some rights reserved. This work is available under the CC BY-NC-SA 3.0 IGO license (https://creativecommons.org/licenses/by-nc-sa/3.0/igo).


The Eastern Mediterranean Region (EMR) confronts unprecedented health challenges, exacerbated by demographic and epidemiologic changes, triple burden of disease, increasing healthcare costs, as well as the effects of contracted emergencies, social conflicts and massive population movements (3-1). Such challenges have repercussions on health care delivery and health research systems. Research for health is essential for developing solutions that contribute to health improvements(4). Investment in research for health contributes to health, economic growth and equity (5).

Well-structured, coordinated and sustainable national research systems are needed to foster development of relevant research for health. Research prioritization is one the four pillars of WHO’s strategy on research for health (6). Other pillars include capacity building, standards and governance, and translation of evidence to policy and practice (7). Research priority setting is essential as it helps identifying the resources needed for research, as well as guiding limited available resources towards issues that matter to maximize the impact of research on population health. This is also key given that there is strong evidence of substantial waste in conduct of research, including conducting research that is not needed, or repeating studies that are not needed anymore (8).

Setting priorities for research can be a complex and tedious process. While different approaches to research prioritization exist, we are not aware of agreement on what might constitute best practice (9-11). Regardless of the variety of approaches followed in the listed experiences, there are minimum criteria to be considered and followed in setting research priorities. As such, countries and large institutions should follow research priority setting approaches that are in tune with their needs, and in line with the expected research plans and funding available for research. They should also be aware of potential barriers to priority setting, and barriers to the implementation of the identified priorities (12).

Studies related to priority setting have been undertaken in a number of low- and middle-income countries (LMIC), using a variety of methods as summarized in a systematic review (13). Others have noted research priorities in the Eastern Mediterranean Region (EMR) in areas related to health systems and policies (14-18). Notably, a study of 10 Arab national health research systems reflected various levels of development and resources, while only 3 reported setting national health research priorities (19). In fact, it is possible that there are more efforts in this area than what meets the eye through published papers, as many priority setting exercises are used for institutional uses (especially those conducted by academic institutions) or are used to announce the call for proposals.

While there may be a need for further national level action on identification of research priorities (19-20), there are also questions on whether such priority settings have resulted in affirmative action on guiding health research. A systematic review of health research priority settings in the Islamic Republic of Iran identified 36 studies, of which only one in four included an implementation plan (21). Calling for research priority setting should always be part of a system approach to conduct needed research for health. A recent study involving over 200 institutions in EMR, indicated that only half reported conduct¬ing research priority-setting exercises, of which only 40% followed a standardized approach and involved policy-makers and stakeholders in setting such priorities. Only a quarter of institutions reported that they examine the extent to which health policy-makers utilize their research results, and a similar number reported measuring the impact of their health research (20,22). Hence, there is still misalignment between national health research priorities and actual research production and use (7).

From WHO standpoint, research priority setting is a key action for enhancing research for health in the EMR, in order to cover the gaps observed through research mapping activities.(20,22-25) As an example, while the Region is disproportionately affected by emergencies, a bibliometric analysis of health research production in the EMR showed scarcity of published research on emergencies (25).

Since 2016, The World Health Organization Regional Office for the Eastern Mediterranean (WHO/EMRO) conducts in-house health research prioritization exercises every two years (26), following a two round priority identification exercise, using Nominal Group Technique for consensus development. Outcomes of such workshops are used to develop the Calls for Proposals for Research in Priority Areas of Public Health (RPPH) small grants and the Tropical Disease Research - Small Grant Scheme (TDR-SGS). The current calls for proposals are now available on the WHO/EMRO website (http://www.emro.who.int/index.html).

In conclusion, health research priority setting assists researchers and policy-makers, in effectively targeting research that has the greatest potential public health benefit, and is increasingly recognized as essential for directing finite resources to support research that maximizes health equity. Priority setting should involve different stakeholders, including policy-makers, which would increase the likelihood of the utilization of research evidence by different partners. Findings of such exercises could inform efforts within and beyond the health sector to better align research objectives and funding, along with the evidence needs of decision-makers contending with questions about how best to achieve universal health coverage (UHC) and health-related Sustainable Development Goals 2030.

References

  1. World Health Organization Regional Office for the Eastern Mediterranean (WHO/EMRO). EMR Vision 2023 Eastern Mediterranean Region. Cairo: WHO/EMRO; 2019 (http://www.emro.who.int/about-who/vision2023/vision-2023.html, accessed 10 March, 2020)
  2. Al-Mandhari A. Public health in the Eastern Mediterranean Region: profound challenges, huge opportunities. Lancet. 2019 Sep 21;394(10203):992-993. DOI: 10.1016/S0140-6736(19)32138-5.
  3. Al-Mandhari A. Achieving “Health for All by All” in the Eastern Mediterranean Region. East Mediterr Health J. 2019 Oct 13;25(9):595-596. DOI: 10.26719/2019.25.9.595.
  4. Editorial: The Bamako call to action: research for health. The Lancet 2008; 372 (9653):1855. DOI: https://doi.org/10.1016/S0140-6736(08)61789-4
  5. World Health Organization. Commission on social determinants of Heath: closing the gap in a generation. Geneva: World Health Organization; 2008.
  6. World Health Organization. WHO strategy on research for health. Geneva: World Health Organization; 2009.
  7. Rashidian A, Mandil A, Mahjour J. Improving evidence informed policy-making for health in the Eastern Mediterranean Region. East Mediterr Health J. 2017;23(12):793-794. DOI: 10.26719/2017.23.10.793.
  8. Chalmers I, Bracken MB, Djulbegovic B, Garattini S, Grant J, Gülmezoglu AM, et al. How to increase value and reduce waste when research priorities are set. Lancet. 2014;383:156-165, DOI: 10.1016/S0140-6736(13)62229-1
  9. Viergever RF, Olifson S, Abdul Ghaffar, Terry RF. A checklist for health research priority setting: nine common themes of good practice. Health Res Policy Syst. 2010;8(36):1-9.
  10. Council on Health Research for Development (COHRED). Essential National Health Research and Priority Setting: Lessons Learned. Manila: COHRED, June 1997.
  11. Fitch K, Bernstein SJ, Aguilar MD, Burnand B, LaCalle JR, Lazaro P, et al. The RAND/UCLA Appropriateness Method User’s Manual. Santa Monica, CA: RAND Corporation; 2001.
  12. Badakhshan A, Arab M, Rashidian A, Mehrdad N, Zendehdel K. Priority-setting in health research in Iran: a qualitative study on barriers and facilitators. Health Res Policy Syst. 2018;16(1):57. DOI: 10.1186/s12961-018-0313-1
  13. McGregor S, Henderson KJ, Kaldor JM. How are health research priorities set in low and middle income countries? A systematic review of published reports. PLoS ONE 2014;9(10): e108787.
  14. El-Jardali F, Makhoul J, Jamal D, Ranson MK, Kronfol NM, Tchaghchagian V. Eliciting policymaker’ and stakeholders’ opinions to help shape health system research priorities in the Middle East and North Africa region. Health Policy Plann. 2010;25:15–27.
  15. Bigdeli M, Javadi D, Hoebert J, Laing R, Ranson K. Health policy and systems research in access to medicines: a prioritized agenda for low- and middle-income countries. Health Res Policy Syst. 2013;11:37
  16. Zaidi S, Bigdeli M, Aleem N, Rashidian A. Access to essential medicines in Pakistan: policy and health systems research concerns. PLoS One. 2013 May 22;8(5):e63515
  17. Gedik FG, Buchan J, Mirza Z, Rashidian A, Siddiqi S, Dussault G. The need for research evidence to meet health workforce challenges in the Eastern Mediterranean Region (Editorial). East Mediterr Health J. 2018;24(9):811-812. DOI: 10.26719.2018.24.9.811.
  18. Mansoori P, Majdzadeh R, Abdi Z, Rudan I, Chan KY, Iranian CHNRI Health Research Priority Setting Group. Setting research priorities to achieve long-term health targets in Iran. J Glob Health. 2018;8(2):020702. DOI: 10.7189/jogh.08.020702
  19. Kennedy A, Khoja T, AbouZeid A, Ghannem H, IJsselmuiden C. National health research system mapping in 10 Eastern Mediterranean countries. East Mediterr Health J. 2008;14(3): 502-517
  20. El-Jardali F, Mandil A, Jamal D, BouKarroum L, El-Feky S, Nour M, et al. Engagement of health research institutions in knowledge translation in the Eastern Mediterranean Region. East Mediterr Health J. 2018;24(7):672–679
  21. Badakhshan A, Arab M, Rashidian A, Gholipour M, Mohebbi E, Zendehdel K. Systematic review of priority setting studies in health research in the Islamic Republic of Iran. East Mediterr Health J. 2018;24(8):753-769. DOI: 10.26719/2018.24.8.753
  22. Mandil A, El-Jardali F, El-Feky S, Nour M, Al-Abbar M, Bou-Karroum L. Health research institutional mapping: an Eastern Mediterranean Regional perspective. East Mediterr Health J. 2018;24(2):189-197
  23. World Health Organization Regional Office for the Eastern Mediterranean (WHO/EMRO). National health research system mapping in the Eastern Mediterranean Region. A study of ten countries. Cairo: WHO/EMRO; 2008
  24. Ghannem H, Becerra-Posada F, IJsselmuiden C, Helwa I, de Haan S. National research for health system mapping in 5 countries in the Eastern Mediterranean region and perspectives on strengthening the systems. East Mediterr Health J. 2011;17(3):260-110.
  25. Tadmouri GO; Mandil A; Rashidian A. Biomedical and health research geography in the Eastern Mediterranean Region (2004–2013). East Mediterr Health J. 2019;25(10).
  26. World Health Organization Regional Office for the Eastern Mediterranean (WHO/EMRO. Workshop on Regional Health Research Priorities, 13 February, 2020, Cairo, Egypt.